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Caspr

Caspr is a contactin-associated protein. Caspr is part of the neurexin family of proteins. Caspr is a membrane protein found in the neuronal membrane in the paranodal section of the axon in myelinated neurons, between the Nodes of Ranvier containing Na+ channels, and juxtaparanode, which contains K+ channels. During myelination, caspr associates with contactin in a cis complex, though its precise role in myelination is not yet understood.

In Western Blotting it has a predicted Molecular Weight around 156 kDa but due to a number of potential glycosylation sites, is 180kDa.