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What is "calumbin"

The Collaborative International Dictionary
Calumbin

Calumbin \Ca*lum"bin\, n. (Chem.) A bitter principle extracted as a white crystalline substance from the calumba root. [Written also colombin, and columbin]

Wiktionary
calumbin

n. (context chemistry English) A bitter principle extracted as a white crystalline substance from the calumba root.