BUF may refer to:
- Amtrak station code for Buffalo-Depew Rail Station in Buffalo, New York
- Baitul Futuh Mosque, London
- Bellingham Unitarian Fellowship, buf.org, A UU congregation in Washington State, USA.
- British Union of Fascists
- BUF Compagnie, a French visual effects company
- Buffalo, New York
- Buffalo Sabres, a National Hockey League (NHL) team, based in Buffalo, New York
- IATA airport code for Buffalo Niagara International Airport, Buffalo, New York
- State University of New York at Buffalo, a public university known as "Buffalo", which sometimes gets shortened to "Buf"