Blandome is a historic home located at Lexington, Virginia. It was built about 1830, and is a two-story, five-bay, Federal / Greek Revival style brick dwelling. It was remodeled in 1872 in the Italianate style. The house features a metal-sheathed hipped roof capped by a belvedere and a three-bay front porch and front entrance with a richly ornamented surround. Also on the property are a contributing seven-sided law office building (c. 1890), garage (c. 1950), and ice chest (c. 1920). Blandome was the home of John Thomas Lewis Preston in the 1830s, who is regarded as the catalyst in the creation of the Virginia Military Institute. It was also the home of John Randolph Tucker (1823-1897) from 1872 to 1875 and again from 1889 until his death in 1897. In 1917, Blandome was acquired by African American business leader Harry Lee Walker, whose wife Eliza Bannister Walker championed numerous social and educational causes.
It was listed on the National Register of Historic Places in 2002.