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Blalock, meaning "dark-haired person" ( Middle EnglishBlakelok), is an English surname. It may refer to:

In medicine:

  • Blalock–Taussig shunt
  • Alfred Blalock, 20th-century American innovator in the field of medical science most noted for his research on the medical condition of shock and the development of the Blalock-Taussig Shunt

In sports:

  • Hank Blalock, Major League baseball third baseman who currently plays for the Texas Rangers
  • Jane Blalock, American professional golfer
  • Justin Blalock, American NFL professional football player
  • Will Blalock, American NBA basketball player

In acting:

  • Jolene Blalock, American actress best known for her role as T'Pol on the television series Star Trek: Enterprise.

In geography:

  • Blalock, Oregon, a former community in the United States