What is "binedaline"

alt. A drug investigated as an antidepressant in the 1980s but never marketed. n. A drug investigated as an antidepressant in the 1980s but never marketed.

Binedaline (Ixprim), also called binodaline, is a drug that was being investigated as an antidepressant in the 1980s but never marketed. It acts as a selective norepinephrine reuptake inhibitor (K = 25 nM), with relatively insignificant influence on the serotonin (K = 847 nM) and dopamine (K >= 2 µM) transporters. It has negligible affinity for the α-adrenergic, mACh, H, or 5-HT receptors.