What is "biacore"

Biacore is a life science products company, based in Sweden. In June 2006 GE Healthcare acquired Biacore for $390 million.

Biacore specializes in measuring biomolecular interactions, including protein-protein interactions, small molecule/fragment-protein interactions, etc. and is often used to measure not only binding affinities, but kinetic rate constants and thermodynamics as well.The technology is based on surface plasmon resonance (SPR), an optical phenomenon that enables detection of unlabeled interactants in real time. The SPR-based biosensors can be used in determination of active concentration as well as characterization of molecular interactions in terms of both affinity and chemical kinetics.