What is "betaxolol"

n. (context medicine English) A topical sympatholytic agent used to reduce ocular hypertension in the treatment of glaucoma

Betaxolol (trade names Betoptic, Betoptic S, Lokren, Kerlone) is a selective beta receptor blocker used in the treatment of hypertension and glaucoma. Being selective for beta receptors, it typically has fewer systemic side effects than non-selective beta-blockers, for example, not causing bronchospasm (mediated by beta receptors) as timolol may. Betaxolol also shows greater affininty for beta receptors than metoprolol. In addition to its effect on the heart, betaxolol reduces the pressure within the eye ( intraocular pressure). This effect is thought to be caused by reducing the production of the liquid (which is called the aqueous humor) within the eye. The precise mechanism of this effect is not known. The reduction in intraocular pressure reduces the risk of damage to the optic nerve and loss of vision in patients with elevated intraocular pressure due to glaucoma.

Betaxolol was approved by the U.S. Food and Drug Administration (FDA) for ocular use as a 0.5% solution (Betoptic) in 1985 and as a 0.25% solution (Betoptic S) in 1989.