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Wiktionary
asplenia

n. Absence of normal spleen function.

Wikipedia
Asplenia

Asplenia refers to the absence of normal spleen function and is associated with some serious infection risks. Hyposplenism is used to describe reduced ('hypo-') splenic functioning, but not as severely affected as with asplenism.

Asplenia (moth)

Asplenia is a genus of moths of the Noctuidae family.