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ASMD may refer to:

  • Addition, subtraction, multiplication and division, the four elementary arithmetic operations
  • Anterior segment mesenchymal dysgenesis, a form of agenesis
  • "ASMD", a code used to refer to the Armstrong Siddeley Double Mamba gas turbine turboprop engine
  • "ASMD", a nuclear defense technology in the Unreal video game series, used mainly with the Shock Rifle