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The Association of the Mediterranean Chambers of Commerce and Industry, in abbreviated form ASCAME, is an organisation of international scope, of a voluntary, non-profit making nature. It unites the Chambers of Commerce and Industry and other similar institutions of the countries of the Mediterranean basin, and works on the assumption that the Black Sea is a natural extension of the Mediterranean Sea.

ASCAME was formed on 1 October 1982. The Constitutive General Assembly was held in Barcelona, hosted by the Barcelona Chamber of Commerce, Industry and Navigation. It is an Organization with a potential membership of 500 Chambers of Commerce, and other associated entities, from the 23 countries bordering the Mediterranean Sea.

Today, ASCAME is the most important representative of the Mediterranean private sector with over 250 Chambers of Commerce from the 23 countries of the Mediterranean basin. ASCAME is a well-consolidated entity that represents the interest of the Mediterranean Chambers of Commerce and the Private Sector, also being accredited as an economic partner of the EU and international organizations in carrying out economic cooperation projects. ASCAME represents all North and South chambers and business regardless of their size and sector of activity.