Wikipedia
The term Antidicomarianites (Greek ἀντιδικοµαριανῖται, literally "opponents of Mary", from ἀντίδικ-ος adversary + Μαρία Mary) was a term used by defenders of the doctrine of the perpetual virginity of Mary during the 4th and 5th centuries. It was pejoratively applied to Christians who believed that the brothers and sisters of Jesus mentioned in the New Testament were not children of Joseph by an earlier marriage — as had become orthodoxy by the 3rd century — but the younger children of Joseph and Mary after the birth of Jesus. There is no evidence that these Christians considered themselves to be "against Mary" in any sense, except of her being the " Queen of Heaven", which Roman Catholics and Orthodox Christians used as a title for her, a reflection of the biblical image in Revelation 12.
Writings against these "Antidicomarianite" Christians — though that name was not yet coined — began in the 3rd century. The earliest reference to this sect appears in Tertullian (c. 160–c. 225), and the doctrines taught by them are expressly mentioned by Origen (185–254). Their views were grounded in mentions of Jesus' brothers and sisters (the desposyni) in the New Testament. The name "Antidicomarianites" was specifically applied to advocates of the doctrine by St. Epiphanius (ca. 315–403), who wrote against them in a letter giving the history of the doctrine and claiming proofs of its falsity. Church writing against the "Antidicomarianites" continued into the 5th century.