What is "allylglycine"

n. A glycine derivative that is an inhibitor of the enzyme glutamate decarboxylase.

Allylglycine is a glycine derivative. It is an inhibitor of the enzyme glutamate decarboxylase. Inhibition of glutamate decarboxylase blocks GABA biosynthesis, leading to lower levels of the neurotransmitter. Allylglycine is known to induce seizures in animals studies, presumably due to this GDC-inhibiting activity.