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AFSA may refer to:

  • The Australian Financial Security Authority
  • The American Federation of School Administrators
  • The American Financial Services Association
  • The Air Force Sergeants Association
  • The Armed Forces Security Agency, precursor to the United States' National Security Agency
  • The American Foreign Service Association
  • Academy For Science and Agriculture (AFSA high school), an agricultural charter school in Vadnais Heights, Minnesota.