Wikipedia
Acid Citrate Dextrose Solution (sometimes called Anticoagulant Citrate Dextrose Solution) is a solution of citric acid, sodium citrate and dextrose in water. It is mainly used as an anticoagulant to preserve blood specimens required for tissue typing, it is also used during procedures such as plasmapheresis instead of heparin. Two different solutions (Solution A and B) are defined by the United States Pharmacopeia.
They have the following properties:
Solution A (per 1000 mL)Total Citrate (as Citric acid, anhydrous (CHO))
20.59 to 22.75g
Dextrose (CHO*HO)
23.28g to 25.73g
Sodium (Na)
4.90g to 5.42g
Solution B (per 1000 mL)Total Citrate (as Citric acid, anhydrous (CHO))
12.37 to 13.67g
Dextrose (CHO*HO)
13.96 to 15.44g
Sodium (Na)
2.94 to 3.25g
To make use:
|
A
B
Citric Acid, anhydrous (CHO)
7.3g
4.4
Sodium Citrate, dihydrate
22.0g
13.2
Dextrose, monohydrate (CHO*HO)
24.5g
14.7
Water for Injection to make
1000 mL
1000 mL
Dissolve the ingredients and mix. Filter until clear.