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Acalabrutinib

Acalabrutinib (rINN, ACP-196) is an experimental anti-cancer drug and a 2nd generation BTK inhibitor developed by Acerta Pharma.

It is designed to be more selective (fewer side-effects) than ibrutinib.

it is in late stage clinical trials for relapsed chronic lymphocytic leukemia. Interim results are encouraging : 95% overall response rate.

It is also in another 20 clinical trials (alone and in combination) for various cancers.