A&D may refer to:
- Akrotiri and Dhekelia, two UK-administered areas on the island of Cyprus that comprise the Sovereign Base Areas military bases of the United Kingdom
- A&D Company, Limited, a Japanese manufacturer of medical equipment and laboratory testing equipment; it refers to "analog and digital"
- Angels & Demons, a book by American author Dan Brown
- Aerospace & Defense, the defense industry
- acquisition and disposition record.