The Collaborative International Dictionary
Wiktionary
conessine
n. A steroid alkaloid found in a number of plant species of the Apocynaceae family, sometimes used in herbal medicine as a treatment for amoebic dysentery.
Wikipedia
Conessine
Conessine is a steroid alkaloid found in a number of plant species from the Apocynaceae family, including Holarrhena floribunda, Holarrhena antidysenterica and Funtumia elastica. It acts as a histamine antagonist, selective for the H subtype (with an affinity of pK = 8.27; K = ~5 nM). It was also found to have long CNS clearance times, high blood-brain barrier penetration and high affinity for the adrenergic receptors.