Crossword clues for apomorphine
The Collaborative International Dictionary
Apomorphia \Ap`o*mor"phi*a\, Apomorphine \Ap`o*mor"phine\, n. [Pref. apo- + morphia, morphine.] (Chem.) A crystalline alkaloid obtained from morphia. It is a powerful emetic. [1913 Webster] ||
Wiktionary
n. (context pharmaceutical drug English) A particular narcotic used in the treatment of Parkinson's disease.
WordNet
n. a morphine derivative that is not as strong as morphine; used as an emetic and in small doses as a sedative
Wikipedia
Apomorphine (brand names Apokyn, Ixense, Spontane, Uprima) is a type of aporphine having activity as a non- selective dopamine agonist which activates both D-like and, to an order of magnitude lesser extent, D-like receptors. It also acts as an antagonist of 5-HT and α-adrenergic receptors with high affinity. The compound is historically a morphine decomposition product by boiling with concentrated acid, hence the -morphine suffix. Apomorphine does not actually contain morphine or its skeleton, nor does it bind to opioid receptors. The apo- prefix relates to it being an morphine derivative ("[comes] from morphine").
Historically, apomorphine has been tried for a variety of uses including psychiatric treatment of homosexuality in the early 20th century, and more recently in treating erectile dysfunction. Currently, apomorphine is used in the treatment of Parkinson's disease. It is a potent emetic (i.e., it induces vomiting) and should not be administered without an antiemetic such as domperidone. The emetic properties of apomorphine are exploited in veterinary medicine to induce therapeutic emesis in canines that have recently ingested toxic or foreign substances.
It was also successfully used as an unofficial treatment of heroin addiction, a purpose for which it was championed by the author William S. Burroughs. A recent study indicates that apomorphine might be a suitable marker for assessing central dopamine system alterations associated with chronic heroin consumption. There is, however, no clinical evidence that apomorphine is an effective and safe treatment regimen for opiate addiction. Early studies involved aversion therapy in alcoholism and anxiety, and modern reports are anecdotal, although some practitioners claimed to be using non-aversive methods.
This is a page of data for apomorphine.
Usage examples of "apomorphine".
Chemists, work round the clock on variation and synthesis of the apomorphine formulae.
I would like to ask you if there could be benign associations-Could you for example associate mescaline with apomorphine on a molecular level?
D, it is in your interest to facilitate our work with the apomorphine formulae?
Nova Police can be compared to apomorphine, a regulating instance that need not continue and has no intention of continuing after its work is done.
Addiction can be controlled by apomorphine and reduced to a minor health problem.
But he provided himself with a stash of apomorphine so escaped and contacted our Tangier agent.