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Answer for the clue "Target of lots of vaccine research ", 3 letters:
hiv

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Word definitions for hiv in dictionaries

Wikipedia Word definitions in Wikipedia
HIV , the human immunodeficiency virus, is a lentivirus that causes acquired immunodeficiency syndrome (AIDS). HIV or Hiv may also refer to:

Douglas Harper's Etymology Dictionary Word definitions in Douglas Harper's Etymology Dictionary
1986, initialism (acronym) from human immunodeficiency virus , name for either of the two viruses that cause AIDS.