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Answer for the clue "Makes a significant change ", 7 letters:
mutates

Alternative clues for the word mutates

Word definitions for mutates in dictionaries

Wiktionary Word definitions in Wiktionary
vb. (en-third-person singular of: mutate )

Usage examples of mutates.

Were mutates the result of the radiation released during the Big Blast, as the Family referred to World War Three, or the consequence of the widespread use of chemical weaponry during the predominantly nuclear war?

He had fought mutates before, many times, but never one of the rarer giants.

As with the mutates, no one knew whether it was a consequence of protracted exposure to enhanced radiation levels, or a genetic imbalance triggered by one of the chemicals employed during the Big Blast, but cases of giantism occurred regularly.

The mutates were bad enough, without having to worry about this new threat.

Plato, the wisest member of the Family, believed the mutates were increasing by geometric progression, and he was eager to secure a live juvenile specimen for analysis.

Three times the gunman stroked each hammer, and after the six shots there were six twitching, dying mutates stretched out on the grass.

When the day comes that the virus mutates its way around this, we may be in real trouble.

DNA with each new generation, and it mutates about twenty times faster than normal nuclear DNA, making it easier to detect and follow genetic patterns over time.