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Something (possibly a virus) triggers an attack on the synovium by the immune system, which releases cytokines that stimulate an inflammatory reaction that can lead to the destruction of all components of the joint
Answer for the clue "Something (possibly a virus) triggers an attack on the synovium by the immune system, which releases cytokines that stimulate an inflammatory reaction that can lead to the destruction of all components of the joint ", 10 letters:
rheumatism
Alternative clues for the word rheumatism
Word definitions for rheumatism in dictionaries
Wikipedia
Word definitions in Wikipedia
Rheumatism or rheumatic disorder is an umbrella term for conditions causing chronic, often intermittent pain affecting the joints and/or connective tissue . The study of, and therapeutic interventions in, such disorders is called rheumatology . The term ...
WordNet
Word definitions in WordNet
n. any painful disorder of the joints or muscles or connective tissues a chronic autoimmune disease with inflammation of the joints and marked deformities; something (possibly a virus) triggers an attack on the synovium by the immune system, which releases ...
The Collaborative International Dictionary
Word definitions in The Collaborative International Dictionary
Rheumatism \Rheu"ma*tism\, n. [L. rheumatismus rheum, Gr. ????, fr.??? to have or suffer from a flux, fr. ??? rheum: cf. F. rheumatisme. See 2d Rheum .] (Med.) A general disease characterized by painful, often multiple, local inflammations, usually affecting ...
Wiktionary
Word definitions in Wiktionary
n. 1 (context pathology English) Any disorder of the muscles, tendons, joints, bones, nerves, characterized by pain, discomfort and disability. 2 (context pathology English) atrophic arthritis, rheumatoid arthritis
Douglas Harper's Etymology Dictionary
Word definitions in Douglas Harper's Etymology Dictionary
c.1600, from Late Latin rheumatismus , from Greek rheumatismos , from rheumatizein "suffer from the flux," from rheuma "a discharge from the body" (see rheum ). "The meaning of a disease of the joints is first recorded in 1688, because rheumatism was thought ...
Usage examples of rheumatism.
A vial of that which is first passed in the morning, should be sent with the history of the case, as chronic rheumatism effects characteristic changes in this excretion, which clearly and unmistakably indicate the abnormal condition of the fluids of the body upon which the disease depends.
It is useful in those diseases in which the fluids of the body are abnormally acid, as in rheumatism.
The relief of the stricture by our new and painless method was followed by very great improvement in his condition, after which appropriate remedies for the rheumatism were administered, and the result was a very gratifying and satisfactory relief from his difficulty.
But most of all, Rae had not suffered a single bout of rheumatism since her discharge from Alameda Hospital.
Acute articular rheumatism implies an affection of the articulations or joints.
Acute articular rheumatism is always accompanied with more or less fever.
Sub-acute articular rheumatism is not always chronic, and may disappear in a shorter time than in the acute form.
Chronic articular rheumatism is not generally fatal, but there is danger of permanent deformities.
Hence, the utmost care should be taken against exposure of a patient recovering from scarlatina, and the same caution should be exercised during convalescence from measles, erysipelas, and rheumatism.
Pityriasis is caused by nutritive debility, and is often associated with erysipelas, rheumatism, and bronchitis.
But what racking pains, on the other hand, arise from gouts, gravels, megrims, toothaches, rheumatisms, where the injury to the animal machinery is either small or incurable?
This feature is very serviceable in distinguishing muscular rheumatism, or myalgia, from neuralgic affections.
A case of this nature is described, the patient being a raftsman, aged seventeen, who suffered with inflammatory symptoms of the right great toe, which were followed in the next ten years by progressive involvement of all the joints of the extremities, and of the vertebrae and temporo-maxillary articulations, with accompanying signs of acute articular rheumatism.
In fact, old Doc Moggs comes around and has a few seidels of hot Tom and Jerry with us for his own rheumatism.
Articular rheumatism, in the subacute or chronic form, is frequently observed in medical practice.