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Answer for the clue "Destruction of tissue by freezing and characterized by tingling, blistering and possibly gangrene ", 9 letters:
cryopathy

Word definitions for cryopathy in dictionaries

WordNet Word definitions in WordNet
n. destruction of tissue by freezing and characterized by tingling, blistering and possibly gangrene [syn: frostbite ]

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
cryopathy \cryopathy\ n. destruction of tissue by freezing and characterized by tingling, blistering and possibly gangrene. Syn: frostbite.