UHC is a three letter acronym that may designate one of the following:
- Universal health care or Universal health coverage
- Unburned hydrocarbon
- Unicorn Hobby Company
- University HealthSystem Consortium
- University Hospital Consortium
- University Hospitals of Cleveland
- Underlying Hazardous Constituent
- Universal Heating Cabinet
- United Healthcare, a large health insurer in the U.S.
- Ultimate Holding Company - An ultimate holding company is a holding company but it is not a subsidiary of any other company.
- Utrecht Haskell Compiler, a Haskell implementation developed by Utrecht University.
- UHC Collective is the name of a radical art collective based in Manchester England who were responsible for the notorious art installation This Is Camp X-Ray
- Unified Hangul Code, Windows code page 949
- UDP Host Cache (used by File sharing networks, like Gnutella)
- United Hospital Center
- Ukrainian Hurts Community