TSX is the Toronto Stock Exchange in Canada.
TSX may also refer to:
- TSX Group, the TMX Group, which owns and operates stock exchanges including the Toronto Stock Exchange
- Acura TSX, an automobile
- Suzuki TSX, a motorcycle
- Triumph T140 TSX, a motorcycle
- Transactional Synchronization Extensions, an extension to the x86 instruction set architecture
- Mubami language (ISO 639 code)