What is "triphenylethylene"

n. (context organic compound English) The triphenyl derivative of ethylene; any derivative of this compound, many of which act as nonsteroidal antiestrogens

Triphenylethylene (TPE) is a simple aromatic hydrocarbon that possesses weak estrogenic properties.

TPE is the parent compound of a group of non-steroidal selective estrogen receptor modulators (SERMs) that includes tamoxifen, clomiphene, chlorotrianisene, DBE, broparestrol, toremifene, droloxifene, idoxifene, ospemifene, fispemifene, and miproxifene, among others.

TPE and its SERM derivatives were derived from structural modification of diethylstilbestrol.