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The Collaborative International Dictionary
To take the name of God in vain

Vain \Vain\, n. Vanity; emptiness; -- now used only in the phrase in vain.

For vain. See In vain. [Obs.]
--Shak.

In vain, to no purpose; without effect; ineffectually. `` In vain doth valor bleed.''
--Milton. `` In vain they do worship me.''
--Matt. xv. 9.

To take the name of God in vain, to use the name of God with levity or profaneness.