What is "thioamide"

n. (context organic chemistry English) Any chemical compound, analogous to the amides in which the oxygen atom of the carbonyl group is replaced by sulfur; R-CS-NH₂ (and N-derivatives)

A thioamide (rarely, thionamide, but also known as thiourylenes) is a functional group with the general structure R–CS–NR′R″, where R, R′, and R″ are organic groups. They are analogous to amides but they exhibit greater multiple bond character along the C-N bond, resulting in a larger rotational barrier. One of the best-known thioamides is thioacetamide, which is used as a source of the sulfide ion and is a building block in heterocyclic chemistry.

Thioamides or anti-thyroid drugs are also a class of drugs that are used to control thyrotoxicosis.