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The Collaborative International Dictionary
Tetra-

Tetra- \Tet"ra-\ [Gr. te`tra-, from te`sares, te`ttares, four. See Four.]

  1. A combining form or prefix signifying four, as in tetrabasic, tetrapetalous.

  2. (Chem.) A combining form (also used adjectively) denoting four proportional or combining parts of the substance or ingredient denoted by the term to which it is prefixed, as in tetra-chloride, tetroxide.

Douglas Harper's Etymology Dictionary
tetra-

before vowels tet-, word-forming element meaning "four," from Greek tetra-, combining form of tettares (Attic), tessares "the numeral four" (see four).

Wiktionary
tetra-

pre. Forming compound words having the sense of ‘four’.