Selenoprotein S, also known as SELS, is a human gene.
Sels is a Belgian surname that may refer to
- Edward Sels (born 1941), Belgian racing cyclist
- Jack Sels (1922–1970), Belgian jazz saxophonist, arranger and composer
- Matz Sels (born 1992), Belgian football player
- Maurits van Löben Sels (1876–1944), Dutch fencer
- Rosa Sels (born 1943), Belgian racing cyclist, sister of Edward