Wikipedia
Sajax
Sajax (Simple Ajax Toolkit), is an open source tool designed to help websites using the Ajax framework (also known as XMLHttpRequest). It allows the programmer to call ASP, ColdFusion, Io, Lua, PHP, Perl, Python, or Ruby functions from their webpages via JavaScript without performing a browser refresh.
Sajax supports IE5+, Pocket IE, Opera 8+ (including mobile), Opera mini 4+, Safari 1.2+, Mozilla 0.94+ and Konqueror.