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quinupristin

n. A streptogramin antibiotic derived from pristinamycin.

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Quinupristin

Quinupristin is an antibiotic, often used in combination with dalfopristin under the trade name Synercid. It is active against Gram-positive bacteria, atypical but not Gram negatives. They inhibit protein synthesis of the cells.' Quinupristin & dalfopristin are not active against Enterococcus faecalis and they need to be given in combination with other antibacterials for mixed infections which also involve Gram negative organisms.'