The Collaborative International Dictionary
Mulligrubs \Mul"li*grubs\, n. [Cf. Prov. E. mull to squeeze, pull about, mulling numb or dull.]
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A griping of the intestines; colic. [Slang]
Whose dog lies sick of the mulligrubs?
--Beau. & Fl. Hence, sullenness; the sulks. [Slang]
Douglas Harper's Etymology Dictionary
"fit of the blues," also "colic," 1590s, mulliegrums, fanciful formation.
Wiktionary
n. 1 (context obsolete English) colic 2 (context slang English) sullenness; sulky behaviour
Wikipedia
Mulligrubs was an Australian television series that aired on Network Ten from 3 October 1988 to 27 December 1996. The series was made by affiliate ADS in Adelaide and was aimed at pre-schoolers.
About 550 episodes were made, with about 425 being stored intact at the National Film and Sound Archive of Australia.
The show was best remembered for the face (made up of just eyes, eyebrows, nostrils and mouth) on a blue screen that appeared occasionally during the program. The actress who played the part of 'the face' was Di Kidd.
Usage examples of "mulligrubs".
All the Van Dams from New York, and the Sleiderheifers and Mulligrubs of New Jersey, were there for the season, some of them in cottages.