MGC can refer to:
- Machine Gun Corps
- Male genital cutting
- Malvern Girls College
- Media Gateway Controller, a device in Voice over IP networks
- Mekong-Ganga Cooperation
- Melbourne Girls' College
- MGC, a British sports car.
- Middle Georgia College
- Midwest Gaming Classic, video game trade show in Wisconsin
- Mississippi Gulf Coast
- Mitsubishi Gas Chemical Company, Inc.
- Museums and Galleries Commission
- The Mircom Group of Companies