Crossword clues for methadone
Longman Dictionary of Contemporary English
The Collaborative International Dictionary
methadon \methadon\, methadone \methadone\n. a narcotic drug similar to morphine but less habit-forming; used in treating heroin addiction.
Syn: methadone hydrochloride.
Douglas Harper's Etymology Dictionary
Wiktionary
n. (context chemistry English) A synthetic opioid analgesic, used to wean addicts off of heroin or other opiate based narcotics, and in chronic pain management.
WordNet
n. synthetic narcotic drug similar to morphine but less habit-forming; used in narcotic detoxification and maintenance of heroin addiction [syn: methadone hydrochloride, methadon, dolophine hydrochloride, fixer, synthetic heroin]
Wikipedia
Methadone, sold under the brand names Dolophine among others, is an opioid used to treat pain and as maintenance therapy or to help with detoxification in people with opioid dependence. Detoxification can either occur relatively rapidly in less than a month or gradually over as long as six months. While a single dose has a rapid effect, maximum effect can take five days of use. The effects last about six hours after a single dose and a day and a half after long-term use. Methadone is taken by mouth or by injection into a muscle or vein.
Side effects are similar to that of other opioids. Commonly these include dizziness, sleepiness, vomiting, and sweating. Serious risks include opioid abuse or a decreased effort to breathe. Heart arrhythmia may also occur including prolonged QT. The number of deaths in the United States involving methadone poisoning was 4,418 in 2011, which was 26% of total deaths from opioid poisoning. Risks are greater with higher doses. Methadone is made by chemical synthesis and acts on opioid receptors.
Methadone was developed in Germany around 1937 to 1939 by Gustav Ehrhart and Max Bockmühl. It was approved for use in the United States in 1947. Methadone is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. Globally in 2013, about 41,400 kilograms were manufactured. It is regulated similarly to other narcotic drugs. In the United States it is not very expensive.
Usage examples of "methadone".
Each bottle arrives with a piece of paper stating that the urine contains no detectable amounts of amphetamines, barbiturates, methadone, opiates, metabolized cocaine, benzodiazepine or THC, the active ingredient in marijuana.
Once-elegant apartment buildings stood next to scrapyards, and where there had been furriers and movie palaces there were now blood banks and methadone clinics and Mother Waddles Perpetual Mission.
No methadone, no help, just me in a room with a bucket and a twelve inch portable colour television that Welsh John stole from a second-hand shop full of previously stolen goods.
Within ten minutes Emma is fast asleep, while I slowly drift off to the two-part background vocals of a cut called "Here's the Deal," which is about either marital infidelity or methadone withdrawal—from the chorus it's impossible to tell.