Mengistu ( Amharic: መንግስቱ) is a male given name of Ethiopian origin that may refer to:
- Mengistu Haile Mariam (born 1937), Ethiopian President and Chairman of the Derg
- Mengistu Worku (1940–2010), Ethiopian football player and coach
- Mengistu Neway (1919–1961), Ethiopian commander of the Imperial Bodyguard
- Mengistu Lemma (1924–1988), Ethiopian playwright and poet.
Category:Ethiopian given names