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Matriptase

Matriptase (, serine protease 14, membrane-type serine protease 1, MT-SP1, prostamin, serine protease TADG-15, tumor-associated differentially-expressed gene 15 protein, ST14, breast cancer 80 kDa protease, epithin, serine endopeptidase SNC19) is an enzyme. This enzyme catalyses the following chemical reaction

Cleaves various synthetic substrates with Arg or Lys at the P1 position and prefers small side-chain amino acids, such as Ala and Gly, at the P2 position

This trypsin-like integral-membrane serine peptidase has been implicated in breast cancer invasion and metastasis.