KWC may refer to:
- Karaoke World Championships, a song contest and talent show
- Kentucky Wesleyan College, a private Methodist college in Owensboro, Kentucky
- Kitchener–Waterloo–Cambridge, a tri-city area in Ontario, Canada.
- King William's College, a school in Castletown, Isle of Man
- Kowloon Walled City, a former enclave of Hong Kong
- Kyocera Wireless Corporation, a manufacturer of mobile phones
- KWC Swiss, a Switzerland company producing taps for home and culinary industry, depending from Hansa Group