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Isochorismatase

In enzymology, an isochorismatase is an enzyme that catalyzes the chemical reaction

isochorismate + HO $\rightleftharpoons$ 2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate

Thus, the two substrates of this enzyme are isochorismate and HO, whereas its two products are 2,3-dihydroxy-2,3-dihydrobenzoate and pyruvate.

This enzyme belongs to the family of hydrolases, specifically those acting on ether bonds (ether hydrolases). The systematic name of this enzyme class is isochorismate pyruvate-hydrolase. Other names in common use include 2,3-dihydro-2,3-dihydroxybenzoate synthase, 2,3-dihydroxy-2,3-dihydrobenzoate synthase, and 2,3-dihydroxy-2,3-dihydrobenzoic synthase. This enzyme participates in the biosynthesis of siderophore group (nonribosomal).