Douglas Harper's Etymology Dictionary
Latin; "within a living organism" (see viva).
Wiktionary
a. Within a living organism. adv. Within a living organism.
WordNet
adj. within a living organism; "in vivo techniques" [ant: in vitro]
adv. in the living organism; "studies conducted in vivo"
Wikipedia
Studies that are in vivo ( Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms, usually animals, including humans, and plants as opposed to a partial or dead organism, or those done in vitro ("within the glass"), i.e., in a laboratory environment using test tubes, petri dishes, etc. Examples of investigations in vivo include: the pathogenesis of disease by comparing the effects of bacterial infection with the effects of purified bacterial toxins; the development of antibiotics, antiviral drugs, and new drugs generally; and new surgical procedures. Consequently, animal testing and clinical trials are major elements of in vivo research. In vivo testing is often employed over in vitro because it is better suited for observing the overall effects of an experiment on a living subject. In drug discovery, for example, verification of efficacy in vivo is crucial, because in vitro assays can sometimes yield misleading results with drug candidate molecules that are irrelevant in vivo (e.g., because such molecules cannot reach their site of in vivo action, for example as a result of rapid catabolism in the liver).
The English microbiologist Professor Harry Smith and his colleagues in the mid-1950s showed the importance of in vivo studies. They found that sterile filtrates of serum from animals infected with Bacillus anthracis were lethal for other animals, whereas extracts of culture fluid from the same organism grown in vitro were not. This discovery of anthrax toxin through the use of in vivo experiments had a major impact on studies of the pathogenesis of infectious disease.
The maxim in vivo veritas ("in a living thing [there is] truth") is used to describe this type of testing and is a play on in vino veritas, ("in wine [there is] truth"), a well-known proverb.
In Vivo is a novel by Mildred Savage. The novel was originally published in hardback by Simon & Schuster in 1964.
In vivo may refer to:
- In vivo, experimentation using a whole, living organism
- In Vivo (novel), a 1964 novel by Mildred Savage
- In Vivo (EP), a 2003 album by rap group Loco Locass
Usage examples of "in vivo".
It seems likely, therefore, that the present examples surviving are mere sexed grubs and that the adult Martian paraprimate does not exist in vivo, though its historical existence is attested by the remarkable examples left of their work.
Only after a possible recombinant had been simulated and overchecked would it finally be tried in vivo.
We've had Hansen's bacillus knocked out a thousand times in the test-tube only to find here that the antibiotic is much more quickly fatal in vivo than is leprosy ftself.
Weve had Hansens bacillus knocked out a thousand times in the test-tube only to find here that the antibiotic is much more quickly fatal in vivo than is leprosy ftself.
The last thing we always do before the in vivo test is to purify the solution using the GEF process.
If it jumps again by the same factor, it's going to swamp our ability to check the immigrants for zimboes in vivo –.