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Douglas Harper's Etymology Dictionary
hypotonic

1873, from hypo- + tonic.

Wiktionary
hypotonic

a. 1 (context of a solution English) Having a lower osmotic pressure than another. 2 (context medicine English) Showing less than normal tension in the muscles or muscle tissue.

WordNet
hypotonic
  1. adj. (of living tissue) lacking normal tone or tension [ant: hypertonic]

  2. (of a solution) having a lower osmotic pressure than a comparison solution [ant: isotonic, hypertonic]