GPAC may refer to
- Geelong Performing Arts Centre, a performing arts, functions, and events venue located in Geelong, Victoria, Australia
- GenderPAC, a gay/lesbian/transgender political action committee based in Washington, D.C.
- Great Plains Athletic Conference, an NAIA college athletic conference in the United States
- GPAC Project on Advanced Content, an Open Source multimedia framework for research and academic purposes in different aspects of multimedia, with a focus on presentation technologies (graphics, animation and interactivity)
- " Give Peace a Chance, a 1969 song by John Lennon
- "Give Peace a Chance" (Grey's Anatomy), a 2009 episode of Grey's Anatomy