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globotriaosylceramide

n. (context biochemistry English) A glycolipid that accumulates in the walls of blood vessels of people with a deficiency of a galactosidase

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Globotriaosylceramide

Globotriaosylceramide is a ganglioside.

It is also known as CD77, Gb3, and ceramide trihexoside. It is one of the few clusters of differentiation that is not a protein.

It is formed by the alpha linkage of galactose to lactosylceramide catalyzed by A4GALT.

It is metabolized by alpha-galactosidase, which hydrolyzes the terminal alpha linkage.