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fosphenytoin

n. A water-soluble phenytoin prodrug used only in hospitals for the treatment of epileptic seizures.

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Fosphenytoin

Fosphenytoin (fosphenytoin sodium injection, previously Cerebyx, Parke-Davis; Prodilantin, Pfizer Holding France) is a water-soluble phenytoin prodrug that is administered intravenously to deliver phenytoin, potentially more safely than intravenous phenytoin. It is most commonly used in the acute treatment convulsive status epilepticus.

Fosphenytoin was developed in 1996. On 18 November 2004, Sicor (a subsidiary of Teva) received a tentative approval letter from the United States Food and Drug Administration for a generic version of fosphenytoin.