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Douglas Harper's Etymology Dictionary
encephalo-

before vowels encephal-, word-forming element meaning "brain, of the brain," from comb. form of medical Latin encephalon, from Greek enkephalos "the brain," literally "within the head," from en "in" (see en- (2)) + kephale "head;" see cephalo-.

Wiktionary
encephalo-

pre. Pertaining to the brain.