What is "ecallantide"

n. A kallikrein inhibitor used for the treatment of hereditary angioedema and for the prevention of blood loss in cardiothoracic surgery.

Ecallantide (trade name Kalbitor, investigational name DX-88) is a drug used for the treatment of hereditary angioedema (HAE) and in the prevention of blood loss in cardiothoracic surgery. It is an inhibitor of the protein kallikrein and a 60- amino acid polypeptide which was developed from a Kunitz domain through phage display to mimic antibodies inhibiting kallikrein.