DPAC may refer to:
- Denver Performing Arts Complex, a collection of performing arts facilities in Colorado.
- Durham Performing Arts Center, a theater in North Carolina.
- Department of Premier and Cabinet (New South Wales)
- Department of the Premier and Cabinet (Queensland)
- Department of Premier and Cabinet, Victoria
- Department of Premier and Cabinet (Western Australia)
- The former Directorate General of Civil Aviation (Drejtoria e Pergjithshme e Aviacionit Civil) of Albania: Albanian Civil Aviation Authority
- The Data Processing and Analysis Consortium of the European Space Agency
- Disabled People Against Cuts