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dose
Longman Dictionary of Contemporary English
dose
I.noun
COLLOCATIONS FROM OTHER ENTRIES
a dose of poison (=an amount of poison)
▪ He had taken a massive dose of poison.
a dose of radiation (=an amount of radiation that someone experiences)
▪ Workers at the site received high doses of radiation.
a dose of reality (=an experience of what things are really like)
▪ I got my first dose of reality when I reported to work at my new job.
lethal dose
▪ a lethal dose of heroin
COLLOCATIONS FROM CORPUS
■ ADJECTIVE
fatal
▪ Digitalis, a heart drug that can be fatal in higher doses, is derived from the foxglove plant.
healthy
▪ A healthy dose of realism does no harm here.
▪ Chrys Chrys recommends a healthy dose of fresh lemon juice squeezed over the fish.
heavy
▪ But given heavy doses of baking soda he began to recover, and was perfectly normal three days later.
▪ Aristotle answered: by inducing heavy doses of pity and terror.
▪ As a result, a heavy dose of reality has descended on the Buchanan campaign.
▪ Of course, tolerance to very heavy doses of caffeine may be problematic for health reasons.
▪ I can't help feeling, therefore, that your critical position relies on a heavy dose of bad faith.
▪ C., a heavy dose of reality is setting in.
high
▪ In the rat, very high single doses of intravenous mesalazine cause acute tubular and papillary necrosis.
▪ Some side effects of high doses include acne, oily skin and insomnia.
▪ It is also true that such high doses have no place in ordinary maintenance drug regimes.
▪ However, the risk of damage for heavier drinkers becomes severe when higher doses of acetaminophen are taken.
▪ Either lower or higher doses are then injected serially until the weal or the symptoms disappear.
▪ The quick, new, high-dose radiation Brachytherapy for cancer patients is also performed at the hospital.
▪ So small volumes of lung tissue are exposed to high doses of alpha radiation.
▪ Most of the psychotic episodes experienced by people using Halcion involved high doses for extended periods of time.
large
▪ In small amounts it can act as a stimulant, in larger doses causing hyperactivity, headaches and insomnia.
▪ In large doses it can cause nausea, vomiting, difficulty breathing and coma.
▪ But most cancers failed to respond at all to the largest doses which were tolerated by healthy tissues.
▪ About that proposition, a large dose of skepticism is in order.
▪ Both single large doses and fractionated doses of radiation have been shown to alter small intestinal motility in animals.
▪ Advocates say that large doses of antioxidants protect against cancer by soaking up dangerous oxygen molecules that can damage cells.
▪ In very large doses they cause stimulation of the central nervous system, convulsions and death.
▪ Such aggregations not only promote transmission of micro-organisms but through repeated exposure allow large doses of these.
lethal
▪ Operators received lethal doses of radiation while needlessly reconnecting the water supply to the devastated reactor.
▪ The prison staff member will then begin to administer lethal doses of three chemicals.
▪ Some workers received lethal doses because the rest of the site was not evacuated.
▪ What effect on pain might, say, three-quarters of the lethal dose have had?
▪ Usually one of Robert's business prospects would be invited for a lethal dose of glamour.
▪ The river still carries a lethal dose of poisons.
▪ Shipman was convicted last year of murdering 15 female patients with lethal doses of diamorphine.
low
▪ Astra refuses to conduct further rat studies with lower doses of ranitidine, saying that this is Glaxo's job.
▪ In low doses, ephedrine speeds up the body, causing restlessness, insomnia, and nervousness.
▪ Either lower or higher doses are then injected serially until the weal or the symptoms disappear.
▪ Another favorable characteristic is that there is a rapid build-up of serum levels, even when starting at low doses.
▪ But they had no low dose folic acid supplements.
▪ Those on moderate or low doses of inhaled steroids showed no increased risk of glaucoma or ocular hypertension.
▪ Generally, lower doses are used than in organ transplantation.
▪ At low to moderate doses, these drugs significantly reduce anxiety without impairing or disrupting other brain systems.
massive
▪ I stayed at home as much as possible while I took massive doses of testosterone, the male hormone.
▪ The most outrageous examples involve force-feeding massive doses of sugar substitutes to white laboratory mice, who eventually grew tumors.
▪ In massive dose, however, 4-ASA may cause haematuria and reduce creatinine clearance, particularly in patients with pre-existing renal disease.
▪ He said he has not been convince d that such a massive dose has much value.
▪ But then the truth about the massive doses of poison which Allitt administered to those babies in her care was uncovered.
mild
▪ It will make the Black Death look like a mild dose of flu.
safe
▪ If there is no safe dose cancer rates should increase as the natural background radiation level increases.
single
▪ In the rat, very high single doses of intravenous mesalazine cause acute tubular and papillary necrosis.
▪ Both single large doses and fractionated doses of radiation have been shown to alter small intestinal motility in animals.
▪ But simpler forms of the drugs, including pills combining more than one drug in a single dose, are becoming available.
▪ Apart from the single ecstasy dose, she believed she had drunk only a glass of wine that night.
▪ In contrast, Rijk etal evaluated the faecal excretions of healthy volunteers with accelerated transit time after a single dose.
▪ The authors claim that single dose treatment has not yet been proved adequate in this context.
▪ There was the high potency, single dose, classical Kentian school, and the low potency, often-repeated school of Hughes.
▪ This shows the insensitivity of single dose comparisons as a method of estimating relative potency.
small
▪ Many of these schemes have been tried before in small doses.
▪ Hence patients requiring smaller doses of levodopa who are troubled with nausea cardiac arrhythmias, or hypotension may use this dosage form.
▪ This can be infectious in small doses, and her catchy anthem, Finally, is pop at its most celebratory.
▪ Life is simple and quiet out here, and even small doses can purify you.
▪ Knock! jokes are okay in small doses - like one every second leap year.
▪ For these individuals the drug must be divided into four or five smaller doses per day.
▪ Problems with diamorphine include vomiting, bradycardia, and hypotension, but in small doses diamorphine is better than any sedative.
▪ Some local attorneys worry about short-term privacy lapses and long-term effects of even small radioactive doses.
standard
▪ In this study, a standard bone sparing dose of oral oestrogen was used.
▪ In contrast, the standard dose of alcohol is measured in liquid ounces.
▪ The standard dose of alcohol is thus roughly 142 times larger than the standard dose of caffeine.
strong
▪ A very strong dose of moral medicine indeed.
▪ The group support offered in diet programs, though, has usually been mixed with a strong dose of group humiliation.
■ VERB
administer
▪ The prison staff member will then begin to administer lethal doses of three chemicals.
give
▪ She was given a dose of Hyper. 30 from her first-aid kit and sent to the neurologist.
▪ So when Casey started public school, first grade, the school nurse had to give him his second dose.
▪ They were given three large doses of vitamin A over a week, and received vitamin A in all subsequent survey rounds.
▪ One tablet or ten tablets taken as one dose still only gives one dose of the potency, does it not?
▪ Aminoglycosides are often given in insufficiently high doses.
▪ Miss T. was given another dose of pethidine.
▪ But some people are allergic to even this highly-purified animal collagen, so potential recipients are first given a small test dose.
▪ A little arsenic can cure disorders of the stomach, but given in regular small doses becomes a poison.
increase
▪ A dose response to oestrogens has been shown with increasing doses having greater effects on bone density.
▪ Many habitual drinkers of caffeine-containing beverages find that they must increase their dose to achieve the preferred degree of stimulation.
▪ Analgesics were given in increasing doses and ascending potency until pain was controlled.
▪ Tolerance means that with regular use, you need to increase the dose to achieve the same effect.
▪ If you are using undergravel filters you will need to increase the dose by 50%.
▪ It is more generally understood as pain that is made worse rather than better by increasing doses of morphine.
▪ In the present study the addition of increasing doses of egg lecithin to human and model biles progressively prolongs the nucleation time.
▪ Biliary lipid composition was not altered significantly but bicarbonate output was increased at all doses tested.
reduce
▪ Thorough revision of laboratory routines could substantially reduce radiation doses received.
▪ In all instances the toxicity was easily reversed by reducing the cyclosporin dose.
require
▪ Repetition of the remedy is continued for as long as is required, and the doses are tailed off gradually.
▪ Hence patients requiring smaller doses of levodopa who are troubled with nausea cardiac arrhythmias, or hypotension may use this dosage form.
▪ Effective analgesia should be administered; the pain is often severe enough to require high dose of morphine or pethidine.
take
▪ One tablet or ten tablets taken as one dose still only gives one dose of the potency, does it not?
▪ The time it takes for a dose of a drug to wear off is measured by a value called a half-life.
▪ Or will he be brave enough to take a dose of poison at the last moment?
▪ She is taking the same dose of medicine that she had received at the hospital.
▪ Plasma concentrations of 5-ASA may therefore be higher in patients taking delayed release mesalazine than in patients taking equivalent doses of sulphasalazine.
▪ Many are taking several times the dose recommended.
▪ I knew she had taken a fine dose.
▪ This time I had to take a double dose to return to my old shape.
use
▪ The necessity for using very high doses of reagents, however, to detect invitro phosphorylation of membranes, is well recognised.
▪ Most of the psychotic episodes experienced by people using Halcion involved high doses for extended periods of time.
▪ If two injections are required, attempting to use the same dose morning and evening may be helpful.
▪ Be sure you are using the appropriate dose however.
▪ Damage to living tissue can be quantified by using the dose equivalent.
▪ If a pesticide has to be used, a smaller dose may be adequate.
▪ Discussion Ascorbic acid has been used in pharmacological doses for more than 20 years.
▪ Transit times were determined using a multiple dose marker technique.
PHRASES FROM OTHER ENTRIES
give sb a dose/taste of their own medicine
EXAMPLES FROM OTHER ENTRIES
▪ The banks need a healthy dose of competition.
EXAMPLES FROM CORPUS
▪ A dose of old-fashioned repression dealt with some of the bold exceptions.
▪ About that proposition, a large dose of skepticism is in order.
▪ Finding such a dose response would have made the case stronger.
▪ She was given a dose of Hyper. 30 from her first-aid kit and sent to the neurologist.
▪ The Cosbys are getting a dose of what families of homicide and fatal accident victims get routinely.
▪ The designation was made because at high doses, alcohol slows down the central nervous system.
▪ The laxative dose required to treat constipation in the young child is much higher than the suggested doses on the label.
II.verb
EXAMPLES FROM CORPUS
▪ Elsie and Edith Port were so alike that Jennie dosed the wrong one with her cure for all ailments - castor oil.
▪ It is generally price advantageous to specify powders although in use they may be more difficult to control and dose.
▪ When the children were ill, she dosed them with herb teas that she brewed herself.
The Collaborative International Dictionary
Dose

Dose \Dose\, v. t. [imp. & p. p. Dosed; p. pr. & vb. n. dosing.] [Cf. F. doser. See Dose, n.]

  1. To proportion properly (a medicine), with reference to the patient or the disease; to form into suitable doses.

  2. To give doses to; to medicine or physic to; to give potions to, constantly and without need.

    A self-opinioned physician, worse than his distemper, who shall dose, and bleed, and kill him, ``secundum artem.'' -- South

  3. To give anything nauseous to.

Dose

Dose \Dose\ (d[=o]s), n. [F. dose, Gr. do`sis a giving, a dose, fr. dido`nai to give; akin to L. dare to give. See Date point of time.]

  1. The quantity of medicine given, or prescribed to be taken, at one time.

  2. A sufficient quantity; a portion; as much as one can take, or as falls to one to receive.

  3. Anything unpleasant that one is obliged to take; a disagreeable portion thrust upon one; also used figuratively, as to give someone a dose of his own medicine, i. e. to retaliate in kind.

    I am for curing the world by gentle alteratives, not by violent doses. -- W. Irving.

    I dare undertake that as fulsome a dose as you give him, he shall readily take it down. -- South.

  4. a quantity of radiation which an object absorbs, or to which it is exposed.

Douglas Harper's Etymology Dictionary
dose

early 15c., "the giving of medicine (in a specified amount or at a stated time)," from Middle French dose (15c.) or directly from Late Latin dosis, from Greek dosis "a portion prescribed," literally "a giving," used by Galen and other Greek physicians to mean an amount of medicine, from stem of didonai "to give" (see date (n.1)). Slang meaning "venereal disease" is from 1914.

dose

1650s, from dose (n.). Related: Dosed; dosing.

Wiktionary
dose

n. 1 A measured portion of medicine taken at any one time. 2 The quantity of an agent (not always active) substance or radiation administered at any one time. vb. 1 to administer a dose 2 to prescribe a dose

WordNet
dose
  1. v. treat with an agent; add (an agent) to; "The ray dosed the paint"

  2. administer a drug to; "They drugged the kidnapped tourist" [syn: drug]

dose
  1. n. a measured portion of medicine taken at any one time

  2. the quantity of an active agent (substance or radiation) taken in or absorbed at any one time [syn: dosage]

  3. street name for lysergic acid diethylamide [syn: acid, back breaker, battery-acid, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen]

Wikipedia
Döse

Döse ( Low German: Döös) the northernmost town in Lower Saxony, Germany at the point where the River Elbe flows into the North Sea. It is a borough of the city Cuxhaven and a popular seaside resort. Döse is located west of Grimmershörn in the borough of Cuxhaven and is one of the tourist centres of the region of Cuxland.

Dose (album)

Dose is the second studio album by Gov't Mule. Te album was released on February 24, 1998, by Volcano Entertainment. It was produced, recorded and mixed by Michael Barbiero and is a much darker record than Gov't Mule's self-titled debut album. The songs "Thelonius Beck" and "Birth of the Mule" were tributes to jazz musicians Thelonious Monk and Miles Davis, respectively.

Dose (magazine)

Dose is a daily Canadian news website and former daily print magazine. It was a mixture of standalone features and coverage of daily news, sometimes from an irreverent perspective. Each daily issue had a theme, and the top margins of every page usually included trivia items related to the theme.

Dose (biochemistry)

A dose is a quantity of something ( chemical, physical, or biological) that may impact an organism biologically; the greater the quantity, the larger the dose. In nutrition, the term is usually applied to how much of a specific nutrient is in a person's diet or in a particular food, meal, or dietary supplement. In medicine, the term is usually applied to the quantity of a drug or other agent administered for therapeutic purposes. In toxicology dose may refer to the amount of a harmful agent (such as a poison, carcinogen, mutagen, or teratogen), to which an organism is exposed.

Chemicals are the most common things for which doses are measured, but there are others, such as radiation exposure. For humans, most doses of micronutrients and medications are measured in milligrams (mg), but some are measured in micrograms because of their potency. Nonmedicinal poisons span the measurement scale; some poisons are so dangerous that a single microgram of it could be deadly, whereas other substances take much more. For example, even water is toxic when consumed in large enough quantities.

Dose (disambiguation)

Usage examples of "dose".

As such minute doses of the salts of ammonia affect the leaves, we may feel almost sure that Drosera absorbs and profits by the amount, though small, which is present in rainwater, in the same manner as other plants absorb these same salts by their roots.

Manner of performing the experiments--Action of distilled water in comparison with the solutions--Carbonate of ammonia, absorbed by the roots--The vapour absorbed by the glands--Drops on the disc--Minute drops applied to separate glands--Leaves immersed in weak solutions--Minuteness of the doses which induce aggregation of the protoplasm--Nitrate of ammonia, analogous experiments with--Phosphate of ammonia, analogous experiments with--Other salts of ammonia--Summary and concluding remarks on the action of salts of ammonia.

A good dose of sugar, or more carbon dioxide, will increase the acidosis enough to put you right.

Rummel, a well-known writer of the same school, speaks of curing a case of jaundice in thirty-four days by Homoeopathic doses of pulsatilla, aconite, and cinchona.

Now, Ferguson, to put your charges against Rochester in concrete form, you believe that he was insanely jealous of Jimmie Turnbull, that he recognized him in the Police Court in his burglar disguise, slipped a dose of aconitine in a glass of water which Turnbull drank, and after declaring that his friend had died from angina pectoris, disappeared.

McIntyre contends that Turnbull forged the letter and stole the securities, then fearing his guilt would become known, committed still another crime - that of suicide, he could have swallowed a dose of aconitine while at the police court.

Four hours at least had to elapse before the fatal dose of aconitine could take effect - four hours!

Farleyfile system would break down if I attempted to mix with crowds, not to mention the unknown hazards of the Actionist goon squads--what I would babble with a minim dose of neodexocaine in the forebrain none of us liked to think about, me least of all.

Farleyfile system would break down if I attempted to mix with crowds, not to mention the unknown hazards of the Actionist goon squads-what I would babble with a minim dose of neodexocaine in the forebrain none of us liked to think about, me least of all.

They sat together over a wheel, which was unfortunate, but at least Jan was not Kate, and had no need of acupressure bracelets and a large dose of Sturgeron.

He was, however, a morphine addict, so seriously addicted that by the time he stood trial atNuremberghe was dosing himself with up to a hundred pills of paracodeine a day.

Another subtle aspect of addiction is that, although it is the first dose that hooks us, the whole process is usually so subtle and gradual that it can take years for us to realize that we are actually hooked.

As expected, they contained two main components: harmless colourants or flavourings designed to make them look or taste good, and doses of addictive narcotics.

The only difference between the schools is in the remedies employed, the size of dose administered, and the results attained.

This agent may be administered in doses of from five to ten drops, largely diluted in water or gruel.