Wiktionary
alt. (context pharmaceutical drug English) One of the stereoisomers of amphetamine, with the chemical formula C9H13N, that is used to stimulate the central nervous system. n. (context pharmaceutical drug English) One of the stereoisomers of amphetamine, with the chemical formula C9H13N, that is used to stimulate the central nervous system.
WordNet
Wikipedia
Dextroamphetamine (American English) or dexamfetamine (Commonwealth English) is a potent central nervous system (CNS) stimulant and amphetamine enantiomer that is prescribed for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. It is also used as an athletic performance and cognitive enhancer, and recreationally as an aphrodisiac and euphoriant. Dextroamphetamine is also widely used by military air forces as a 'go-pill' during fatigue-inducing mission profiles such as night-time bombing missions. Preparations containing dextroamphetamine were also used in World War II as a treatment against fatigue.
The amphetamine molecule exists as two enantiomers (i.e., two different molecules that are mirror images of one another), levoamphetamine and dextroamphetamine. Dextroamphetamine is the more active dextrorotatory, or 'right-handed', enantiomer of the amphetamine molecule. Pharmaceutical dextroamphetamine sulfate is available as both a brand name and generic drug in a variety of dosage forms. Dextroamphetamine is sometimes prescribed as the inactive prodrug lisdexamfetamine dimesylate, which is converted into dextroamphetamine after absorption.
Dextroamphetamine, like other amphetamines, elicits its stimulating effects via several distinct actions: it inhibits or reverses the transporter proteins for the monoamine neurotransmitters (namely the serotonin, norepinephrine and dopamine transporters) either via trace amine-associated receptor 1 (TAAR1) or in a TAAR1 independent fashion when there are high cytosolic concentrations of the monoamine neurotransmitters and it releases these neurotransmitters from synaptic vesicles via vesicular monoamine transporter 2. It also shares many chemical and pharmacological properties with human trace amines, particularly phenethylamine and , the latter being an isomer of amphetamine produced within the human body.
Usage examples of "dextroamphetamine".
He drank steadily and, when he remembered to, popped green time-release capsules of dextroamphetamine plus amobarbital.
He called Williard and had him send a bottle of dextroamphetamine to his first sergeant, who loved the pills for the extra energy they gave him.
Amphetamines are broken down chemically into three types: salts of racemic amphetamines, dextroamphetamines, and methamphetamines, which only differ in potencies.