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Clazakizumab

Clazakizumab (formerly ALD518 and BMS-945429) is an aglycosylated, humanized monoclonal antibody against interleukin-6. It is an investigational drug for cancer and rheumatoid arthritis due to its anti-inflammatory properties.

The relatively long half-life of about 30 days should allow less frequent and subcutaneous injections.

It is made using yeast cells rather than the standard Chinese hamster ovary cells.